Gold Nanoparticles & Smart Delivery

Gold nanoparticles (AuNPs) possess unique properties that make them highly valuable in biomedical applications. They can be synthesized in various shapes (spheres, rods, cages, shells) and sizes, which affect their optical and biological behavior; for instance, gold nanorods absorb near-infrared light, useful for deep tissue imaging and photothermal therapy. Their gold surface allows easy attachment of molecules like drugs, targeting ligands (antibodies, peptides), polymers, and imaging agents, enabling precise functionalization for specific therapeutic uses. Additionally, AuNPs are generally biocompatible and inert, with their stability in the body improved by coatings such as polyethylene glycol (PEG), which also helps extend their circulation time in the bloodstream.